MedQuest Cream Bases

Why Does the Cream Base Formula Matter?

Active pharmaceutical ingredients often steal the spotlight. Understandably so, finding the proper drug and dose to address unique therapeutic challenges is essential

How a drug is delivered to the body can be just as important. The total package matters, including the selected formula base. 

Customized bases are a key component of compounded topical and vaginal therapy. While traditional products have standard limitations, compounding pharmacies like MedQuest create space for providers and patients to tailor medications to fit individual needs 

Ellage® Anhydrous Vaginal and VersaPro® Cream offer distinctive benefits, targeting different areas of the body. 

Get to Know Ellage® Anhydrous Vaginal

The What
 

  • Ellage Anhydrous Vaginal is designed to transform into a micro-emulsion when mixed with vaginal fluid, that allows for the release of active ingredients into the mucosa. These active ingredients are then trapped in the vaginal tissue by design, prolonging drug exposure and benefit potential. 
  • Ellage Anhydrous Vaginal is an opaque, non-water containing base, compatible with multiple active ingredients.  
  • The formulation feels smooth to the touch and is free of wheat, milk, egg, soy, fish, peanut, almond, pecan, macadamia, walnut, hazelnut, and gluten. 

The Where 

  • Ellage Anhydrous Vaginal is uniquely constructed for vaginal application.  
  • Base composition encourages mucosal adhesion that can readily release active ingredients into vaginal tissue due to its design as a self-emulsifying drug delivery formulation.  
  • Per extensive studies performed by manufacturer PCCA, Ellage Anhydrous Vaginal can promote bioavailability of hormones like estradiol and testosterone when in contact with small volumes of vaginal fluid.  

The Why 

  • Debilitating vaginal symptoms deserve uncompromising support. Vaginal preparations should be tough enough to thoroughly penetrate the vaginal mucosa while being gentle on damaged, dry tissue.  
  • While some vaginal preparations can leak or struggle to stick, the base’s composition specifically combats these barriers to therapy. Ellage Anhydrous Vaginal offers a non-irritating vehicle designed to deliver the prescribed active ingredients directly to the sensitive sites that need it most. 

Get to Know VersaPro® Cream

The What

  • VersaPro Cream is a white, shiny, oil-in-water moisturizing base designed for transdermal drug delivery. Formulated with vitamin E and aloe vera, it feels non-greasy and appears pharmaceutically elegant.  
  • VersaPro Cream is a water containing base, compatible with lipophilic and hydrophilic drugs in both base and salt form.  
  • The formulation is hypoallergenic and free of parabens, mineral oil, and petrolatum. See the product’s allergen declaration to learn more.  

The Where 

  • VersaPro Cream is a versatile base with a multipurpose design, appropriate for topical, vaginal, or cosmetic delivery.  
  • Its non-greasy and non-comedogenic makeup allows VersaPro Cream to be a strong option regardless of intended site of action.  

The Why 

  • VersaPro Cream is a reliable multipurpose vehicle, considered compatible with a range of active pharmaceutical ingredients. 
  • While some bases can be compromised when compounding medications with a high ingredient load, VersaPro Cream performs comfortably at high capacity.  
  • Per extensive studies performed by its manufacturer Medisca®, VersaPro Cream can penetrate the skin barrier to promote permeability of hormones like progesterone. 

All products compounded for vaginal or topical administration are typically dispensed in a Topi-CLICK Perl® or Pump device.

Click below to learn more about drug delivery devices.

  1. VersaPro Cream Base.” Medisca, www.medisca.com/products/versapro-cream-base. Accessed August 2024. 
  2. PCCA. Ellage® Anhydrous Vaginal, 2023, https://www.pccarx.com/. Accessed August 2024.